: Princeton researcher Britt Adamson, together with collaborators, developed improvements to high-throughput technologies that can be used to explore how cells respond to experimentally-induced changes in gene expression. Continue Reading →
A study published in the journal Nature Microbiology identified factors that the hepatitis B virus uses when establishing long-term infection in the liver. The findings could help lead to treatment strategies for chronic HBV infection, a condition that increases the risk of developing liver cancer and is responsible for almost 900,000 deaths worldwide each year. Continue Reading →
Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning, and how genetic mutations alter the enzymes’ behavior in ways that cause disease, including cancer. Continue Reading →
Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube. Continue Reading →
A new technology can automatically track animals’ body parts in video to measure the behavior of animals. Continue Reading →
A Princeton-led team has decoded the impact of a new class of mutations in people with autism. Continue Reading →
The team examined 22 years of psychological, sociological and demographic data from more than 338,000 respondents in 100+ countries. Continue Reading →
Researchers studied the courtship behaviors of fruit flies to gain insight into how the brain creates “internal states” which culminate from mood, past experiences and other variables. Continue Reading →
A new study yields insights into how an organelle called the pyrenoid, which helps algae remove carbon dioxide from the atmosphere, forms inside the cell via a process similar to how oil separates from water. Continue Reading →
Princeton University researchers have developed a new, scalable cell culture system that allows for detailed investigation of how host cells respond to infection with hepatitis B (HBV) and delta virus (HDV). The paper describing their Continue Reading →
Princeton University researchers have discovered that learned behaviors in worms of the species C. elegans can be inherited for multiple generations, transmitted from parent to progeny via eggs and sperm cells. The paper detailing this Continue Reading →
Over the course of a school year, elementary school children lose confidence that they can “be scientists,” but remain more confident that they can “do science,” finds a new psychology study by researchers at New Continue Reading →
Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection. The report, led Continue Reading →
T cells are like the special ops forces of the immune system, detecting and killing infected cells. When a new threat is detected, the cells ramp up from just a few sentry cells to a Continue Reading →
Asking young girls to “do science” leads them to show greater persistence in science activities than does asking them to “be scientists,” finds a new psychology study by researchers at New York University and Princeton Continue Reading →
By Kevin McElwee Only about 10 percent of the human genome are actually genes. The other 90 percent? Once called “junk DNA,” researchers now know that this genetic material contains on-off switches that can activate Continue Reading →
By Yasemin Saplakoglu MOLECULAR BIOLOGIST MIKE LEVINE likes to recall his childhood when he talks about the reason he came to Princeton. “I grew up near Hollywood and I always loved movies as a kid, so Continue Reading →
By Yasemin Saplakoglu A collaborative approach to sociology aims to target fundamental and perhaps overlooked issues to improve policies that affect the lives of disadvantaged children. The effort, called the Fragile Families Challenge, brings together Continue Reading →
By Pooja Makhijani A new study has identified genetic changes that are linked to dogs’ human-directed social behaviors and suggests there is a common underlying genetic basis for hyper-social behavior in both dogs and humans. Continue Reading →
By Yasemin Saplakoglu When Daniel D. Liu first encountered the world of research, he saw giants in white lab coats shaking flasks and squirting liquids into small vials. He was 4 years old, and his Continue Reading →
SOMETIMES, TO SURVIVE, our cells destroy their own ribonucleic acid (RNA), the part of our genetic instruction code that helps turn genes into proteins. Cells do this as part of the first line of defense Continue Reading →
By Bennett McIntosh One hundred years ago, Italian chemist Giacomo Ciamician predicted a future society that would run on sunlight. In a paper presented in 1912 to an international meeting of chemists in New York Continue Reading →
Some drugs cannot be delivered via a normal pill or injection because they cannot readily dissolve in water. About 40 percent of new pharmaceuticals have this hydrophobic (water-fearing) character, and like a globule of oil Continue Reading →
TO EXPLORE HOW THE BRAIN controls behavior, researchers have for the first time captured the whole-brain activity of a freely moving animal, in this case a nematode worm called Caenorhabditis elegans. Using an imaging system Continue Reading →
INSIDE OUR CELLS, TINY FACTORIES convert nutrients from food into a form of energy that cells can use. Failure of these factories, known as mitochondria, can lead to metabolic disorders that are difficult to diagnose Continue Reading →
BACTERIA SPEAK TO ONE ANOTHER using a soundless language known as quorum sensing. In a step toward translating bacterial communications, researchers have revealed the structure and biosynthesis of streptide, a signaling molecule involved in the Continue Reading →
THE MEASLES VIRUS can lead to serious disease in children by suppressing their immune systems for up to three years, according to a study published in the journal Science on May 8, 2015. The study Continue Reading →
By Takim Williams RED-HOT RIVERS OF MOLTEN COPPER and aluminum alloys streamed from one receptacle to another. As an undergraduate watching the demonstration in a materials science class, Clifford Brangwynne was reminded of cells migrating Continue Reading →
FLOCKS OF BIRDS FLY ACROSS THE SKY in shifting configurations. In the retina of an eye, millions of neurons ignite in ever-changing combinations, translating light into meaningful images. Yet both of these seemingly random behaviors Continue Reading →
RADIOACTIVITY IS USUALLY ASSOCIATED with nuclear fallout or comic-book spider bites, but in very small amounts it can be a useful tool for diagnosing diseases. Small molecules containing a radioactive isotope of fluorine, called 18F, Continue Reading →
AS AN UNDERGRADUATE, Angelina Sylvain was fascinated to learn that devastating declines in cognition and muscle coordination could be caused by changes in a single gene — the cause of Huntington’s disease. She was intrigued Continue Reading →
Evolution, often perceived as a series of random changes, might in fact be driven by a simple and repeated genetic solution to an environmental pressure, according to new research. “Is evolution predictable? To a surprising Continue Reading →