Mathematical model reveals behavior of cellular enzymes

Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning, and how genetic mutations alter the enzymes’ behavior in ways that cause disease, including cancer. Continue Reading →

Researchers unlock secrets of cell division, define role for protein elevated in cancer

Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube. Continue Reading →

How hepatitis B and delta viruses establish infection of liver cells

Princeton University researchers have developed a new, scalable cell culture system that allows for detailed investigation of how host cells respond to infection with hepatitis B (HBV) and delta virus (HDV). The paper describing their Continue Reading →

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection. The report, led Continue Reading →

BONNIE BASSLER receives Shaw Prize in life science and medicine

Bonnie Bassler, the Squibb Professor in Molecular Biology and chair of the Department of Molecular Biology, was named a 2015 Shaw Laureate in life science and medicine on June 1, 2015. Awarded by the Hong Continue Reading →

How to train your worm to explore the circuits involved in learning

AS AN UNDERGRADUATE, Angelina Sylvain was fascinated to learn that devastating declines in cognition and muscle coordination could be caused by changes in a single gene — the cause of Huntington’s disease. She was intrigued Continue Reading →

Captured on video: Virus-sized particle trying to enter cell

RESEARCHERS AT PRINCETON UNIVERSITY achieved an unprecedented look at a virus-like particle as it tries to break into and infect a cell. The video reveals the particle zipping around in a rapid, erratic manner until Continue Reading →

Small RNAs fight cancer’s spread

Cancer patients may benefit from a dual strategy for tackling their disease in a class of molecules called microRNAs. Molecular biology graduate student Brian Ell has revealed that microRNAs — small bits of genetic material Continue Reading →

Princeton role in federal BRAIN initiative

Princeton neuroscientists are poised to play a leading role in revolutionizing our understanding of the human brain as outlined in President Barack Obama’s BRAIN Initiative, announced in April 2013. David Tank, co-director of the Princeton Continue Reading →

Princeton biologist Bonnie Bassler receives L’Oréal-UNESCO For Women in Science award

Bonnie Bassler, the Squibb Professor in Molecular Biology and a Howard Hughes Medical Institute Investigator, was among five scientists worldwide selected to receive the 2012 For Women in Science Award presented by UNESCO and cosmetics Continue Reading →