Mathematical model reveals behavior of cellular enzymes

Mathematical modeling helps researchers to understand how enzymes in the body work to ensure normal functioning, and how genetic mutations alter the enzymes’ behavior in ways that cause disease, including cancer. Continue Reading →

Researchers unlock secrets of cell division, define role for protein elevated in cancer

Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube. Continue Reading →

New progress in developing an animal model of hepatitis C

Small differences in a liver cell protein have significant impacts on hepatitis C virus replication in mice and humans, findings that could facilitate the development of a mouse model of the infection. The report, led Continue Reading →

How cancer stem cells evade the immune system

By Yasemin Saplakoglu When Daniel D. Liu first encountered the world of research, he saw giants in white lab coats shaking flasks and squirting liquids into small vials. He was 4 years old, and his Continue Reading →

In cells, self-destructive behavior suggests strategy for fighting cancer

SOMETIMES, TO SURVIVE, our cells destroy their own ribonucleic acid (RNA), the part of our genetic instruction code that helps turn genes into proteins. Cells do this as part of the first line of defense Continue Reading →

No more mirrors: a new way of making molecules for tracking disease

RADIOACTIVITY IS USUALLY ASSOCIATED with nuclear fallout or comic-book spider bites, but in very small amounts it can be a useful tool for diagnosing diseases. Small molecules containing a radioactive isotope of fluorine, called 18F, Continue Reading →

Small RNAs fight cancer’s spread

Cancer patients may benefit from a dual strategy for tackling their disease in a class of molecules called microRNAs. Molecular biology graduate student Brian Ell has revealed that microRNAs — small bits of genetic material Continue Reading →